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KMID : 1034320130040020051
Sleep Medicine Research
2013 Volume.4 No. 2 p.51 ~ p.55
Pattern of Hypnotic Drug Prescription in South Korea: Health Insurance Review and Assessment Service-National Patients Sample
Chung Seok-Hoon

Park Bo-Ram
Yi Ki-Kyoung
Lee Joong-Sun
Abstract
Background and Objective: This study aimed to characterize patterns of hypnotic drug prescription based on age and gender using data from the Health Insurance Review and Assessment Service-National Patients Sample (HIRA-NPS) of South Korea.

Methods: Using HIRA-NPS data, the ¡°number of tablets of equivalent hypnotic drugs (TEQ)¡± was defined herein as the number of tablets of triazolam, zolpidem immediate-release form, or zolpidem extended-release form.

Results: The proportion of hypnotic medication prescriptions, including triazolam and zolpidem, was 1.47% in the sample population. The proportion was significantly higher among women than men (1.63% vs. 1.29%; p < 0.01). In addition, the proportion of subjects who were prescribed hypnotic drugs increased with age. The mean TEQ per year was significantly higher among women in the 30?39 year old group (p = 0.02), but lower in women of the 70?79 year old group compared to men (p = 0.04). Of the subjects prescribed the drugs, 14.53% were prescribed at least 0.5 TEQ per day, while 5.0% were given at least 1.0 TEQ per day 0.6% at least 2.0 TEQ per day. Such cases were most common among middle-aged patients (30?59 years old).

Conclusions: The proportion of hypnotic drug prescriptions increased with patient age and in females. However, the total amount of hypnotics prescribed per year was greatest among males and middle-aged patients.
KEYWORD
Hypnotics, Zolpidem, Insomnia, Dependence
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